4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE
- Product Name
- 4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE
- CAS No.
- 164391-47-3
- Chemical Name
- 4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE
- Synonyms
- Zinc00005777;Immepip hydrobromide;IMMEPIP DIHYDROBROMIDE;4-(1H-Imidazol-5-ylmethyl)piperidine hydrobromide;4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE;Piperidine,4-(1H-imidazol-4-ylmethyl)-,dihydrobromide
- CBNumber
- CB4459345
- Molecular Formula
- C9H17Br2N3
- Formula Weight
- 327.06
- MOL File
- 164391-47-3.mol
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Property
- Melting point:
- 234-235℃
- storage temp.
- 2-8°C
- solubility
- H2O: 7 mg/mL at <40 °C
- form
- solid
- color
- light tan
- Water Solubility
- Soluble to 100 mM in water
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- I4034
- Product name
- Immepip dihydrobromide
- Purity
- ≥97% (HPLC), powder
- Packaging
- 10mg
- Price
- $204
- Updated
- 2024/03/01
- Product number
- I4034
- Product name
- Immepip dihydrobromide
- Purity
- ≥97% (HPLC), powder
- Packaging
- 50mg
- Price
- $646
- Updated
- 2024/03/01
- Product number
- 29518
- Product name
- Immepip (hydrobromide)
- Packaging
- 1mg
- Price
- $33
- Updated
- 2024/03/01
- Product number
- 29518
- Product name
- Immepip (hydrobromide)
- Packaging
- 5mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- 29518
- Product name
- Immepip (hydrobromide)
- Packaging
- 10mg
- Price
- $160
- Updated
- 2024/03/01
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Chemical Properties,Usage,Production
Description
Immepip is a histamine H3 receptor agonist (KI = 0.4 nM in SK-N-MC cell membranes expressing the human receptor). It is selective for histamine H3 over H1 and H2 receptors in CHO cell membranes expressing the guinea pig and human receptors, respectively (Kis = >16 μM for both) but also agonizes H4 receptors (KI = 9 nM in SK-N-MC cell membranes expressing the human receptor). Immepip (5 mg/kg, s.c.) decreases hypothalamic histamine release in anesthetized rats. It decreases flinching in the formalin test in rats when administered at doses of 5 and 30 mg/kg and inhibits formalin-induced paw edema at 30 mg/kg.
Chemical Properties
Crystalline Solid
Uses
A selective nonchiral histamine H3 agonist.
Biological Activity
Potent histamine H 3 receptor agonist. Also binds to H 4 receptors (K i values are 0.4 and 9 nM at human recombinant H 3 and H 4 receptors respectively). Equipotent to or slightly more active than (R)- α -methylhistamine at H 3 receptors.
storage
Desiccate at RT
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Suppliers
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